Monthly Archives: March 2017

Dr. Perry Sheffield Featured in JAMA Article About Climate Change Health Effects

On March 22, 2017, P30 Center Member Perry Sheffield was featured in The Journal of the American Medical Association’s (JAMA) article “Medical Community Gathers Steam to Tackle Climate’s Health Effects.” The article recommends for health professionals to combat climate-related health dangers.

Dr. Sheffield’s week-long course on global health for first-year medical students at The Icahn School of Medicine at Mount Sinai was highlighted. In the course, Dr. Sheffield covers climate change and each year, 1 or 2 Mount Sinai students also conduct research on climate change and health. In one project, Dr. Sheffield said, a student examined how New York City’s extreme heat preparedness activities meet the needs of its elderly populations. Dr. Sheffield also is working on a climate change curriculum project with medical educators who represent about 9 medical schools. They’re addressing the call for increased medical education on the topic, a subject that Mount Sinai’s medical education department supports. To read the full article click here. 

“Identifying sensitive windows for prenatal particulate air pollution exposure” paper featured in NIEHS Newsletter

Allan Just, PhD

Rosalind Wright, MD

Robert Wright, MD, MPH











In March 2017, P30 Center Member’s paper “Identifying sensitive windows for prenatal particulate air pollution exposure and mitochondrial DNA content in cord blood” was featured in NIEH’S Environmental Factor Papers of the Month. The study involved participants in the NIH-funded Programming Research in Obesity, Growth, Environment, and Social Stressors cohort in Mexico City. The researchers measured the mitochondrial DNA content of white blood cells in umbilical cord blood collected from mothers at delivery.

P30 Center Members found that increased prenatal exposure to particulate matter less than 2.5 micrometers (PM2.5) during a specific portion of the third trimester may increase oxidative stress and susceptibility to health effects mediated by white blood cells, such as infections and immune response to allergens. During this window in late pregnancy, increased exposure to PM2.5 air pollution was associated with lower mitochondrial DNA content in cord blood, a marker of oxidative stress. Oxidative stress is an imbalance in the production of free radicals and the body’s ability to counteract their harmful effects. To read the full article click here.