Dr. Arora’s Autism and Tooth Study Featured in New York Times Article

On July 02, 2018, Drs. Manish Arora and Paul Curtin were featured in NYT Article “In Baby Teeth, Links Between Chemical Exposure in Pregnancy and Autism” to discuss the association of past environmental exposures and autism. Dr. Arora and a team of researchers developed an innovative technique using baby teeth, which start to develop toward the end of the first trimester, and form a new layer each day, growing in what he called an “incremental archival manner.” The layers can capture traces of chemicals, so that they serve as “biologic hard drives,” records of what exposures occurred during fetal development, and when they occurred, in a manner similar to the rings on trees. Using the teeth that children have shed between the ages of 6 and 12, Dr. Arora said, it’s possible to look back at exposures during fetal development, and at other aspects of early metabolism to see whether children who later go on to develop autism are biologically different early on. In a study published in Science Advances in May, scientists used this technique to compare early zinc and copper metabolism in children with autism with their siblings without autism.Dr. Arora said this could lead to a biomarker for autism, a diagnostic test which could be administered before a child shows behavioral differences. To read more click here.